Anti-HER2 (clone IC5R22D) SynExpress E1-Cy3-NF-B CD4+ T Cells

CAT#: ITS-1124-CR583
Clone: IC5R22D
Host: Mouse
Cell Source: Synthetic CD4+ T cells
Species Reactivity: Human
Connector Fragments: EF1α-Cy3-NF-κB-BamHI
Carrier Type: AAV
Description
This product utilizes CD4+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target HER2 ( clone IC5R22D). We employs the AAV (EF1α-Cy3-NF-κB-BamHI) vector components and the SynExpress system of the lncRNA Base Editing/Delayed feedback for a robust and sustained response against cancers.
Host
Mouse
Target
HER2
Clone
IC5R22D
Species Reactivity
Human
Cell Source
Synthetic CD4+ T cells
Sensor Gene
Cy3
Promoter
EF1α
Effector Gene
NF-κB
Insertion Sites
BamHI
Gene Modification
Base Editing
Modification Domain
lncRNA
Carrier Type
AAV
Transformation Accuracy
0.89
Cell Culture
Suspension Culture
Target
HER2
Alternative Names
ERBB2; CD340; HER-2; HER-2/neu; HER2; MLN 19; NEU; NGL; TKR1; erb-b2 receptor tyrosine kinase 2
Gene ID
P27930(Human)
UniProt ID
2064(Human); 13866(Mouse)
Format
Lyophilized/Liquid
Shipping
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.
For Research Use Only | Not For Clinical Use
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