Anti-HMGB1 (clone 31G5L9Q) SynExpress E1-R-β-E NK cells

CAT#: ITS-1224-CR185
Clone: 31G5L9Q
Host: Mouse
Cell Source: NK cells
Species Reactivity: Human; Mouse
Connector Fragments: EF1α-RFP-β-catenin-EcoRI
Carrier Type: Lentivirus
Description
This product utilizes NK cells that have been engineered with our proprietary GeneCircuit technology to specifically target HMGB1 (clone 31G5L9Q). We employs the Lentivirus (EF1α-RFP-β-catenin-EcoRI) vector components and the SynExpress system of the Single base pair Knockout/Adaptive feedback for a robust and sustained response against cancers.
Host
Mouse
Target
HMGB1
Clone
31G5L9Q
Species Reactivity
Human; Mouse
Cell Source
NK cells
Sensor Gene
RFP
Promoter
EF1α
Effector Gene
β-catenin
Insertion Sites
EcoRI
Gene Modification
Knockout
Modification Domain
Single base pair
Carrier Type
Lentivirus
Transformation Accuracy
0.85
Cell Culture
Suspension Culture
Target
HMGB1
Alternative Names
HMGB1; HMG1; HMG3; SBP-1; HMG-1; high mobility group box 1; HMGB-1
Gene ID
P24822(Mouse)
UniProt ID
3146(Human); 100862258(Mouse); 15289(Rat)
Format
Lyophilized/Liquid
Shipping
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.
For Research Use Only | Not For Clinical Use
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