Creative Biolabs-Immuno-oncology

Anti-LAG3 (clone Ab3) SynExpress C-BF-I4-X Modified CD8+ T cells (CAT#: ITS-1224-CR1988)

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Description
This product utilizes Modified CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target LAG3 (clone Ab3). We employs the Retrovirus (CMV-BFP-IL-4-XbaI) vector components and the SynExpress system of the Single base pair Knockout/Negative feedback for a robust and sustained response against cancers.
Host
Humanized
Target
LAG3
Clone
Ab3
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
BFP
Promoter
CMV
Effector Gene
IL-4
Insertion Sites
XbaI
Gene Modification
Knockout
Modification Domain
Single base pair
Carrier Type
Retrovirus
Transformation Accuracy
0.86
Cell Culture
Adherent Culture
Case Studies
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