PharmaOnco™ CHO-Tg(Human SLAMF7) Stable Cell Line, Single Clone

Creative Biolabs offers CHO-Tg(Human SLAMF7) stable cell line which the SLAMF7 gene stably expressed in CHO cells.

CHO-Tg(Human SLAMF7) stable cell line is a cell line derived from Chinese hamster ovary (CHO) cells that have been genetically modified to express the human SLAMF7 gene. SLAMF7, also known as CS1, is a cell surface glycoprotein that is expressed on natural killer cells and a subset of T cells. It plays a role in cell adhesion and signaling. CHO-Tg(Human SLAMF7) stable cell line can be used for various applications in research and drug development, such as screening for SLAMF7-targeted therapeutics, studying the role of SLAMF7 in immune cell function, and investigating the interaction between SLAMF7 and its ligands.

Consistent gene expression;
Reliability and reproducibility;

Functional assay

SLAMF7

Human

CHO

Genbank #NM_021181

SLAMF7 (Signaling Lymphocytic Activation Molecule Family member 7) is a gene that encodes a cell surface receptor protein involved in the regulation of immune responses. SLAMF7 is primarily expressed on natural killer (NK) cells, plasma cells, and a subset of T cells. It plays a role in cell adhesion, activation, and cytotoxicity in the immune system. Mutations in the SLAMF7 gene have been associated with various immune system disorders, including autoimmune diseases and immunodeficiencies. Targeting SLAMF7 with monoclonal antibodies has shown promise as a treatment for multiple myeloma, a type of blood cancer that affects plasma cells.

1 x 10e6 cells/vial, Frozen

Creative Biolabs provides sterility testing in accordance with USP and EP regulations. All of our sterility testing is performed in an isolator or clean room environments. The cell line has been screened using the membrane filtration testing methods to confirm the absence of aerobic, anaerobic and fungi microorganisms.

Identity testing is required for newly established cell lines. Isoenzyme analysis is used to confirm the identity of the species of a cell line. Alternative methods for identity testing include DNA fingerprinting, STR analysis and karyology.

A broad range of viruses is susceptible to affecting human cell lines. We can provide in vivo/vitro virus safety assays by utilizing various animal systems. These viruses include: adventitious viruses, bovine viruses, human and simian viruses, porcine viruses, retrovirus and rodent viruses.

We perform cell genetic stability studies under ICH guidelines. We can provide guidance on the appropriate testing program upon your requirements.

The cell line has been screened using the luciferase based mycoplasma detection kit to confirm the absence of mycoplasma species.

Dry Ice

Frozen cells should be stored in a liquid nitrogen tank (-150°C~-190°C). After thawing, cells should be immediately transferred to the appropriate culture medium and maintained under recommended culture conditions.

Frozen cells should be thawed immediately upon receipt and grown according to handling procedure to ensure cell viability and proper assay performance.
Note: Do not freeze the cells upon receipt as it may result in irreversible damage to the cell line.
Disclaimer: We cannot guarantee cell viability if the cells are not thawed immediately upon receipt and grown according to handling procedure.

Avoid multiple freeze/thaw cycles

For research use only, not for diagnostic or therapeutic use.

All of our stable cell lines meet the highest quality standards and have been confirmed to be pathogen-free.