PharmaOnco™ Jurkat-NFAT eGFP Reporter Cell Line, Single Clone (CAT#: ITS-0822-HMM184)

Creative Biolabs offers Jurkat-NFAT eGFP reporter cell line which has been engineered to express a reporter gene eGFP under the control of the NFAT promoter.

The Jurkat-NFAT eGFP reporter cell line is a specific type of cell line that has been engineered to express a reporter gene called enhanced green fluorescent protein (eGFP) under the control of the nuclear factor of activated T-cells (NFAT) promoter. NFAT is a transcription factor that plays a key role in regulating the activation of T-cells, which are important immune cells involved in the body's defense against infections and diseases. This cell line is often used in studies to investigate the molecular mechanisms underlying T-cell activation, signaling pathways, and immune responses.

Consistent gene expression;
Reliability and reproducibility;

Functional assay

Jurkat

NFAT eGFP reporter is a genetic construct that includes the Nuclear Factor of Activated T-cells (NFAT) promoter region linked to the enhanced green fluorescent protein (eGFP) gene. This reporter system is commonly used in cell biology research to monitor cellular activity of NFAT, a transcription factor that plays a critical role in regulating immune response and other biological processes. When activated, NFAT translocates to the nucleus and induces expression of eGFP, resulting in fluorescent signal that can be easily visualized and quantified using fluorescence microscopy or flow cytometry. The NFAT eGFP reporter system provides a convenient tool for studying NFAT activation dynamics in living cells and investigating the signaling pathways that control NFAT activity.