Short Description
Specific quantification of acetoacetate (ketone body).
Development Stage
Research-Grade Metabolic Assay Development
Description
The OXPHOSight™ Acetoacetate Assay Kit specifically quantifies acetoacetate, distinguishing it from other ketone bodies to provide precise monitoring of diabetic ketoacidosis. This assay supports clinical trials for ketogenic diets and metabolic therapies by tracking acute shifts in fatty acid oxidation. It is essential for evaluating the safety and efficacy of drugs that influence ketogenesis.
Features
Specific for acetoacetate (does not detect beta-hydroxybutyrate); Precise monitoring of ketoacidosis in clinical trials.
Process Relevance
Metabolic Monitoring (Ketosis)
Application Stage
Clinical Research
Applications
Monitoring ketosis in diabetes and ketogenic diet studies.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Absorbance at 550 nm
Sample Type
Serum, plasma, urine, and other biological samples
Research Areas
Diabetes & Obesity; Endocrinology
Datasheet