Biotinylated Human IL-6 R alpha Protein (Leu 20-Pro 365) [Avi] [His] (VAng-1619Lsx)
Biotinylated Human IL-6 R alpha protein, Avi tag and His tag, expressed in human 293 cells. (Uniprot ID: P08887-1)
Datasheet
Specifications
Source
HEK293 Cells.
Target
IL6R
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
PBS, pH 7.4.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
IL6R is a type I cytokine receptor. It is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. The IL6 receptor is a protein complex consisting of an IL-6 receptor subunit (IL6R) and interleukin 6 signal transducer Glycoprotein 130. IL6R also denotes the human gene encoding this subunit. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alternative Names
IL6R, CD126, IL-6R-1, IL-6RA, IL6RA, IL-6R-alpha, IL6RQ, gp80
Related Product
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
