Recombinant Axl Protein (Ala 26-Pro 449) [His] (VAng-1082Lsx)
Human Axl, His tag, is expressed in HEK 293 cells. (Uniprot ID: AAH32229)
Applications
SDS-PAGE; WB; ELISA.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Introduction
Axl (AXL Receptor Tyrosine Kinase) is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene.
Alternative Names
AXL, UFO
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