Recombinant Human Axl Protein (Baculovirus) (VAng-3437Lsx)

Baculovirus

Axl

Tumor Antigens

SDS-PAGE; WB; ELISA.

PBS, pH 7.4.

> 95% pure by SDS-PAGE.

Store at -20°C to -80°C.

Axl (AXL Receptor Tyrosine Kinase) is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene.

AXL, UFO