ACO2-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR40
Cell Type: MDSCs
RNA writers: METTL3
RNA readers: YTHDF1
RNA erasers: FTO
Enzymes: HDACs
RNA types: mRNAs
Modification: m5C
RNA editing: T to C
Short Description
This product is a ACO2-targeted RNA modification and metabolomics analysis tool based on the m5C (METTL3-YTHDF1-FTO-HDACs-TET) modification and Gluconeogenesis-mediated (MBNL-SAM-ATP) metabolic analysis system.
RNA writers
METTL3
RNA readers
YTHDF1
RNA erasers
FTO
Enzymes
HDACs
RNA types
mRNAs
Modification
m5C
Label
TET
RNA editing
T to C
Cell Type
MDSCs
Oligonucleotide
2'-OMe, 2'dT (LNP)
RNA Construction
mRNAs-m5C-METTL3-YTHDF1-FTO-HDACs-TET
Substrates
SAM
Cofactors
ATP
Pathway
Gluconeogenesis
Epigenetic regulator
SMARCA4 overexpression
Metabolic alteration
Upregulating fatty acids synthesis
Targeting diseases
Adrenocortical carcinoma
RNA-binding proteins
MBNL
Metabolic Reprogramming
Gluconeogenesis-MBNL-SAM-ATP
Target
ACO2
Alternative Names
ACO2; ACONM; ICRD; OCA8; HEL-S-284; OPA9; aconitase 2
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
Online Inquiry