Creative Biolabs-Immuno-oncology

Anti-CD70 (clone MDX-1G4I1G1G) SynExpress SP-mCh-I10-X Synthetic CD4+ T cells (CAT#: ITS-1224-CR1771)

DatasheetDatasheet
Description
This product utilizes Synthetic CD4+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target CD70 (clone MDX-1G4I1G1G). We employs the pGEX (SP6-mCherry-IL-10-XbaI) vector components and the SynExpress system of the Multiple base pair Insertion/Positive feedback for a robust and sustained response against cancers.
Host
Human
Target
CD70
Clone
MDX-1G4I1G1G
Species Reactivity
Human
Cell Source
Synthetic CD4+ T cells
Sensor Gene
mCherry
Promoter
SP6
Effector Gene
IL-10
Insertion Sites
XbaI
Gene Modification
Insertion
Modification Domain
Multiple base pair
Carrier Type
pGEX
Transformation Accuracy
0.86
Cell Culture
Adherent Culture
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For Research Use Only | Not For Clinical Use

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