Anti-GRP78 (clone B4I) SynExpress C-G-TF-E NK cells

CAT#: ITS-1224-CR1072
Clone: B4I
Host: Humanized
Cell Source: NK cells
Species Reactivity: Human
Connector Fragments: CMV-GFP-TFIIA-EcoRI
Carrier Type: pGEM
Description
This product utilizes NK cells that have been engineered with our proprietary GeneCircuit technology to specifically target GRP78 (clone B4I). We employs the pGEM (CMV-GFP-TFIIA-EcoRI) vector components and the SynExpress system of the Multiple base pair Knockout/Adaptive feedback for a robust and sustained response against cancers.
Host
Humanized
Target
GRP78
Clone
B4I
Species Reactivity
Human
Cell Source
NK cells
Sensor Gene
GFP
Promoter
CMV
Effector Gene
TFIIA
Insertion Sites
EcoRI
Gene Modification
Knockout
Modification Domain
Multiple base pair
Carrier Type
pGEM
Transformation Accuracy
0.88
Cell Culture
Microcarrier Culture
Target
GRP78
Alternative Names
HSPA5; BIP; GRP78; HEL-S-89n; MIF2; Binding immunoglobulin protein; heat shock protein family A (Hsp70) member 5; GRP78/Bip
Gene ID
P02771(Human); P02772(Mouse); P02773(Rat)
UniProt ID
3309(Human); 14828(Mouse); 25617(Rat)
Format
Lyophilized/Liquid
Shipping
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.
For Research Use Only | Not For Clinical Use
Online Inquiry