This product utilizes Modified CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target MERTK (clone M2E1G). We employs the Retrovirus (pBAD-mNeonGreen-LEF/TCF-EcoRI) vector components and the SynExpress system of the lncRNA Base Editing/Positive feedback for a robust and sustained response against cancers.
Host
Human
Target
MERTK
Clone
M2E1G
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
mNeonGreen
Promoter
pBAD
Effector Gene
LEF/TCF
Insertion Sites
EcoRI
Gene Modification
Base Editing
Modification Domain
lncRNA
Carrier Type
Retrovirus
Transformation Accuracy
0.95
Cell Culture
3D Culture
Target
MERTK
Alternative Names
MERTK; MER; RP38; c-mer; Tyro12; c-Eyk; MER proto-oncogene; tyrosine kinase
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.