Assay Type: Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Overview
This assay is to provide C2BBe1-based In Vitro SYTOX Assay (Cell Viability) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
C2BBe1
Target Cell Organism
Human
Target Cell Background
The C2BBe1 (brush border expressing) cell line was cloned in 1988 from the Caco-2 cell line by limiting dilution. The clone was selected on the basis of morphological homogeneity and exclusive apical villin localization.
Related Diseases
Colorectal Adenocarcinoma; Colon Cancer
Research Area
Oncology
Assay Name
In Vitro SYTOX Assay (Cell Viability)
Short Description
C2BBe1-cell based In Vitro SYTOX Assay (Cell Viability)
Assay Description
The dyes in SYTOX family (blue, green, orange and red), TOTO and TO-PRO are other fluorescence dyes, which can penetrate only into dead cells to determine the cell viability.
Assay Type
Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Type Details
Uncontrolled proliferation is one of the main features of cancer cells. Cell-based in vitro assays are employed to determine whether test molecules possess direct cytotoxic/antiproliferative effects in cancer cells.