C6 In Vitro Ferric Reducing-antioxidant Power Assay (Oxidative Stress)
CAT#: ITS-1022-YF5012
Target Cell Organism: Rat
Target Cell Name: C6
Assay Type: Oxidative Stress Assays
Assay Overview
This assay is to provide C6-based In Vitro Ferric Reducing-antioxidant Power Assay (Oxidative Stress) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
C6
Target Cell Organism
Rat
Target Cell Background
c6 is a rat glioma cell line.
Related Diseases
Glioblastoma
Research Area
Oncology
Assay Name
In Vitro Ferric Reducing-antioxidant Power Assay (Oxidative Stress)
Short Description
C6-cell based In Vitro Ferric Reducing-antioxidant Power Assay (Oxidative Stress)
Assay Description
It's a commonly used simple antioxidant assay. The reduction of a ferric complex to ferrous ions by potential antioxidants is the main principle of the ferric reducing-antioxidant power assay.
Assay Type
Oxidative Stress Assays
Assay Type Details
Disturbance between the production of reactive oxygen species (ROS), free radicals and antioxidant mechanisms is defined as the oxidative stress, or more precisely, it is an imbalance between the oxidant and antioxidant state in cells. This imbalance can cause harmful effects to cells and biomolecules, which ultimately causes adverse effects in the whole organism. Oxidative imbalance can target important proteinsand lipids in cells, which can increase the risk of developing a cancer. On the other hand, increased ROS production in cancer cells by certain cancer drugs can also arrest cancer cell cycle and cause senescence and apoptosis through oxidative stress.