CCRF-CEM In Vitro BrdU Assay (Cell Proliferation)

CAT#: ITS-1122-YF5054
Target Cell Organism: Human
Target Cell Alternative Name: CCRF CEM
Target Cell Name: CCRF-CEM
Assay Type: Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Overview
This assay is to provide CCRF-CEM-based In Vitro BrdU Assay (Cell Proliferation) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
CCRF-CEM
Target Cell Organism
Human
Target Cell Background
CCRF-CEM [CCRF CEM] are human T lymphoblasts isolated from the peripheral blood of a female, Caucasian 4-year-old with acute lymphoblastic leukemia (ALL). This cell line is used for immuno-oncology and immunology research.
Target Cell Alternative Name
CCRF CEM
Related Diseases
Acute Lymphoblastic Leukemia; ALL
Research Area
Oncology
Assay Name
In Vitro BrdU Assay (Cell Proliferation)
Short Description
CCRF-CEM-cell based In Vitro BrdU Assay (Cell Proliferation)
Assay Description
5-Bromo-2'-deoxyuridine (BrdU) assay is another methodological approach used to determine cell proliferation. BrdU incorporated into synthesized DNA can be determined using BrdU-specific monoclonal antibody. A secondary antibody is used to generate fluorescent sig nal on DNA synthesis.
Assay Alternative Names
5-Bromo-2'-deoxyuridine (BrdU) Assay
Assay Type
Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Type Details
Uncontrolled proliferation is one of the main features of cancer cells. Cell-based in vitro assays are employed to determine whether test molecules possess direct cytotoxic/antiproliferative effects in cancer cells.
Assay Subtype
Cell Proliferation Assay
Assay MOA
Cell-based Assays Based on DNA Synthesis
For Research Use Only | Not For Clinical Use
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