CCRF-CEM In Vitro Resazurin Assay (Cell Viability)

CAT#: ITS-1122-YF5046
Target Cell Organism: Human
Target Cell Alternative Name: CCRF CEM
Target Cell Name: CCRF-CEM
Assay Type: Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Overview
This assay is to provide CCRF-CEM-based In Vitro Resazurin Assay (Cell Viability) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
CCRF-CEM
Target Cell Organism
Human
Target Cell Background
CCRF-CEM [CCRF CEM] are human T lymphoblasts isolated from the peripheral blood of a female, Caucasian 4-year-old with acute lymphoblastic leukemia (ALL). This cell line is used for immuno-oncology and immunology research.
Target Cell Alternative Name
CCRF CEM
Related Diseases
Acute Lymphoblastic Leukemia; ALL
Research Area
Oncology
Assay Name
In Vitro Resazurin Assay (Cell Viability)
Short Description
CCRF-CEM-cell based In Vitro Resazurin Assay (Cell Viability)
Assay Description
Resazurin is a non-fluorescent (blue in color) component of alamar Blue reagents, which can enter viable cells. After entering in to viable cells, resazurin is converted to resorufin by NADH, NAD (P) H or FADH2-dependent cellular oxidore ductase.
Assay Type
Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Type Details
Uncontrolled proliferation is one of the main features of cancer cells. Cell-based in vitro assays are employed to determine whether test molecules possess direct cytotoxic/antiproliferative effects in cancer cells.
Assay Subtype
Cell Viability Assay
Assay MOA
Cell-based Viability Assays Based on Cellular Enzymes and Proteins
For Research Use Only | Not For Clinical Use
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