This assay is to provide CCRF-CEM-based In Vivo Tumorigenesis Assay to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
CCRF-CEM
Target Cell Organism
Human
Target Cell Background
CCRF-CEM [CCRF CEM] are human T lymphoblasts isolated from the peripheral blood of a female, Caucasian 4-year-old with acute lymphoblastic leukemia (ALL). This cell line is used for immuno-oncology and immunology research.
Target Cell Alternative Name
CCRF CEM
Related Diseases
Acute Lymphoblastic Leukemia; ALL
Research Area
Oncology
Assay Name
In Vivo Tumorigenesis Assay
Short Description
CCRF-CEM-cell based In Vivo Tumorigenesis Assay
Assay Description
Tumorigenicity is defined the property of a cell to form tumors when inoculated into an immunosuppressed animal model. Generally, test cells and tumor cells as positive control are administered subcutaneously into immunosuppressed nude mice. The number of animals developing tumors are compared with a positive control reference cell line.