CelluTest™ Tryptophan Assay Kit

CAT#: ITS-1125-HM55
Product Type: Assay Kit
Species: All Species
Brand: CelluTest
Development Stage: Research-Grade Cellular Function Assay Development
Short Description
Quantifies tryptophan levels using a fluorometric method.
Brand
CelluTest
Development Stage
Research-Grade Cellular Function Assay Development
Description
The CelluTest™ Tryptophan Assay Kit quantifies tryptophan levels to monitor indoleamine 2,3-dioxygenase (IDO) activity, a key target in cancer immunotherapy. This fluorometric assay supports the development of IDO inhibitors by tracking tryptophan depletion in the tumor microenvironment. It is essential for researching immune escape mechanisms and optimizing combination therapies in oncology.
Features
No extraction required; High-throughput measurement of IDO activity in cancer immunotherapy development.
Process Relevance
Immuno-Oncology Target Validation (IDO)
Application Stage
Lead Optimization
Applications
Investigating serotonin synthesis and IDO pathway activity in cancer.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Fluorescence Detection (Ex 530 nm / Em 585 nm)
Sample Type
Serum
Research Areas
Immuno-Oncology; Neuroscience
Size
100 tests
Data Output Type
Quantitative (Concentration)
Assay Time
Results in 30 min
LOD
10 µM
Species
All Species
Storage
Store at −20 °C upon receipt to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to −20 °C storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
6 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Tryptophan is an essential amino acid and precursor for serotonin. Its catabolism via the kynurenine pathway is a major mechanism of immune tolerance and is often upregulated in tumors to suppress T-cells.
For Research Use Only | Not For Clinical Use
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