Short Description
Quantifies tryptophan levels using a fluorometric method.
Development Stage
Research-Grade Cellular Function Assay Development
Description
The CelluTest™ Tryptophan Assay Kit quantifies tryptophan levels to monitor indoleamine 2,3-dioxygenase (IDO) activity, a key target in cancer immunotherapy. This fluorometric assay supports the development of IDO inhibitors by tracking tryptophan depletion in the tumor microenvironment. It is essential for researching immune escape mechanisms and optimizing combination therapies in oncology.
Features
No extraction required; High-throughput measurement of IDO activity in cancer immunotherapy development.
Process Relevance
Immuno-Oncology Target Validation (IDO)
Application Stage
Lead Optimization
Applications
Investigating serotonin synthesis and IDO pathway activity in cancer.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Fluorescence Detection (Ex 530 nm / Em 585 nm)
Research Areas
Immuno-Oncology; Neuroscience
Datasheet