CT26.WT In Vitro High-throughput Screening (HTS) Assay

This assay is to provide CT26.WT-based In Vitro High-throughput Screening (HTS) Assay to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.

CT26.WT

Mouse

CT26 is an N-nitroso-N-methylurethane-(NNMU) induced, undifferentiated colon carcinoma cell line. It was cloned to generate the cell line designated CT26.WT. Use CT26.WT mouse fibroblasts with CT26.CL25 as a model for testing immunotherapy protocols and in studies on the host immune response.

CT26

Colorectal Adenocarcinoma; Colon Cancer

Oncology

In Vitro High-throughput Screening (HTS) Assay

CT26.WT-cell based In Vitro High-throughput Screening (HTS) Assay

HTS is one of the modern technologies used in cancer drug discovery. This technique enables to screen or assay thousands of chemical compounds against a target of interest within a short period. HTS is also useful in screening different libraries such as synthetic compounds, combinatorial chemistry, peptides and genomic libraries and obtaining toxicological and pharmacokinetic data related to chemical compounds. HTS has gained much attention among scientists and industries as a large number of compounds prepared by chemical synthesis methods can be screened within a short period, which can reduce the cost of drug discovery and animal use. HTS consist of major steps such as identification of targets, preparation of reagents, management of test compounds, development of suitable assay procedures and screening.

High-throughput Screening, High Content Screening and Reporter Gene Assays