CUTLL1 In Vitro Glutathione Assay (Oxidative Stress)

CAT#: ITS-1122-YF5635
Target Cell Organism: Human
Target Cell Name: CUTLL1
Assay Type: Oxidative Stress Assays
Assay Overview
This assay is to provide CUTLL1-based In Vitro Glutathione Assay (Oxidative Stress) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
CUTLL1
Target Cell Organism
Human
Target Cell Background
The CUTLL1 cell line was established from pleural effusion of a relapsed 14-year-old male patient suffering from T-cell lymphoblastic lymphoma.
Related Diseases
Acute Lymphoblastic Leukemia; ALL
Research Area
Oncology
Assay Name
In Vitro Glutathione Assay (Oxidative Stress)
Short Description
CUTLL1-cell based In Vitro Glutathione Assay (Oxidative Stress)
Assay Type
Oxidative Stress Assays
Assay Type Details
Disturbance between the production of reactive oxygen species (ROS), free radicals and antioxidant mechanisms is defined as the oxidative stress, or more precisely, it is an imbalance between the oxidant and antioxidant state in cells. This imbalance can cause harmful effects to cells and biomolecules, which ultimately causes adverse effects in the whole organism. Oxidative imbalance can target important proteinsand lipids in cells, which can increase the risk of developing a cancer. On the other hand, increased ROS production in cancer cells by certain cancer drugs can also arrest cancer cell cycle and cause senescence and apoptosis through oxidative stress.
Assay Subtype
Markers Thiobarbituric Acid Reactive Substances
For Research Use Only | Not For Clinical Use
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