DND-41 In Vitro TO-PRO Assay (Cell Viability)

CAT#: ITS-1122-YF5166
Target Cell Organism: Human
Target Cell Name: DND-41
Assay Type: Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Overview
This assay is to provide DND-41-based In Vitro TO-PRO Assay (Cell Viability) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
DND-41
Target Cell Organism
Human
Target Cell Background
DND-41 was established from the peripheral blood of 13-year-old boy with T-acute lymphoblastic leukemia (T-ALL; type III cortical) in 1977; described to carry CDKN2B (p15INK4B) and CDKN2A (p16INK4A) deletions and TP53 (p53)mutation.
Related Diseases
Acute Lymphoblastic Leukemia; ALL
Research Area
Oncology
Assay Name
In Vitro TO-PRO Assay (Cell Viability)
Short Description
DND-41-cell based In Vitro TO-PRO Assay (Cell Viability)
Assay Description
The dyes in SYTOX family (blue, green, orange and red), TOTO and TO-PRO are other fluorescence dyes, which can penetrate only into dead cells to determine the cell viability.
Assay Type
Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Type Details
Uncontrolled proliferation is one of the main features of cancer cells. Cell-based in vitro assays are employed to determine whether test molecules possess direct cytotoxic/antiproliferative effects in cancer cells.
Assay Subtype
Cell Viability Assay
Assay MOA
Dye Exclusion Assays
For Research Use Only | Not For Clinical Use
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