Assay Type: Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Overview
This assay is to provide E.G7-OVA-based In Vitro EdU Assay (Cell Proliferation) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
E.G7-OVA
Target Cell Organism
Mouse
Target Cell Background
E.G7-OVA [derivative of EL4] T lymphoblasts are T lymphoblasts derived in 1988 from the C57BL/6 (H-2 b) mouse lymphoma cell line EL4. E.G7-OVA [derivative of EL4] is a model system for studying major histocompatibility complex (MHC) class I restricted responses of cytotoxic T lymphocytes in mice.
Related Diseases
Lymphoma
Research Area
Oncology
Assay Name
In Vitro EdU Assay (Cell Proliferation)
Assay Description
5-Ethynyl-2'-deoxyuridine (EdU) can easily be com bined with DNA during replication. Unlike the BrdU assay, the EdU assay is rapid, sensitive and does not require previous denaturation of the specimen.
Assay Alternative Names
5-Ethynyl-2'-deoxyuridine (EdU) Assay
Assay Type
Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Type Details
Uncontrolled proliferation is one of the main features of cancer cells. Cell-based in vitro assays are employed to determine whether test molecules possess direct cytotoxic/antiproliferative effects in cancer cells.