Assay Type: Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Overview
This assay is to provide FaDu-based In Vitro Resazurin Assay (Cell Viability) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
FaDu
Target Cell Organism
Human
Target Cell Background
FaDu is a cell line with epithelial morphology that was established in 1968 from a punch biopsy of a hypopharyngeal tumor removed from a 56-year-old, White, male patient with squamous cell carcinoma. This cell line is a suitable transfection host and has applications in cancer and immuno-oncology research.
Related Diseases
Squamous Cell Carcinoma
Research Area
Oncology
Assay Name
In Vitro Resazurin Assay (Cell Viability)
Short Description
FaDu-cell based In Vitro Resazurin Assay (Cell Viability)
Assay Description
Resazurin is a non-fluorescent (blue in color) component of alamar Blue reagents, which can enter viable cells. After entering in to viable cells, resazurin is converted to resorufin by NADH, NAD (P) H or FADH2-dependent cellular oxidore ductase.
Assay Type
Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Type Details
Uncontrolled proliferation is one of the main features of cancer cells. Cell-based in vitro assays are employed to determine whether test molecules possess direct cytotoxic/antiproliferative effects in cancer cells.
Assay Subtype
Cell Viability Assay
Assay MOA
Cell-based Viability Assays Based on Cellular Enzymes and Proteins