Short Description
Quantifies total heme in biological samples.
Development Stage
Research-Grade Oxidative Stress Assay Development
Description
The GuardianOx™ Heme Assay Kit utilizes a detergent-based lysis method to clear turbidity, allowing for the accurate validation of drugs affecting heme biosynthesis. This assay is critical for research into porphyrias and anemia, measuring total heme levels in blood and tissue. It supports the assessment of drug candidates that may interfere with heme pathways or induce heme oxygenase activity.
Features
Detergent-based lysis clears turbidity; Validates drugs affecting heme biosynthesis and porphyria treatments.
Process Relevance
Hematotoxicity Screening
Application Stage
Discovery
Applications
Studying heme biosynthesis disorders and porphyrias.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Absorbance at 400 nm
Sample Type
Blood, serum, plasma, urine samples
Research Areas
Hematology; Porphyrias
Datasheet