GuardianOx™ Heme Assay Kit

CAT#: ITS-1125-HM80
Product Type: Assay Kit
Species: All Species
Brand: GuardianOx
Development Stage: Research-Grade Oxidative Stress Assay Development
Short Description
Quantifies total heme in biological samples.
Brand
GuardianOx
Development Stage
Research-Grade Oxidative Stress Assay Development
Description
The GuardianOx™ Heme Assay Kit utilizes a detergent-based lysis method to clear turbidity, allowing for the accurate validation of drugs affecting heme biosynthesis. This assay is critical for research into porphyrias and anemia, measuring total heme levels in blood and tissue. It supports the assessment of drug candidates that may interfere with heme pathways or induce heme oxygenase activity.
Features
Detergent-based lysis clears turbidity; Validates drugs affecting heme biosynthesis and porphyria treatments.
Process Relevance
Hematotoxicity Screening
Application Stage
Discovery
Applications
Studying heme biosynthesis disorders and porphyrias.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Absorbance at 400 nm
Sample Type
Blood, serum, plasma, urine samples
Research Areas
Hematology; Porphyrias
Size
250 tests
Data Output Type
Quantitative (Concentration)
Assay Time
Results in 5 min
LOD
0.6 µM
Species
All Species
Storage
Store at 4 °C upon receipt to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.
Storage Comment
Avoid freezing unless otherwise specified. During use, minimize prolonged exposure to room temperature and return components promptly to 2-8 °C storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
12 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Heme is an iron-containing porphyrin essential for oxygen transport. Disturbances in heme synthesis lead to porphyrias while free heme is toxic and pro-inflammatory inducing tissue damage.
For Research Use Only | Not For Clinical Use
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