HCT-116 In Vitro Ethidium Homodimer Assay (Cell Viability)
CAT#: ITS-1022-YF5902
Target Cell Organism: Human
Target Cell Name: HCT-116
Assay Type: Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Overview
This assay is to provide HCT-116-based In Vitro Ethidium Homodimer Assay (Cell Viability) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
HCT-116
Target Cell Organism
Human
Target Cell Background
HCT 116 cell line was isolated from the colon of an adult male with colon cancer. It has a mutation in codon 13 of the ras proto-oncogene and can be used as a positive control for PCR assays of mutation in this codon.
Related Diseases
Colorectal Adenocarcinoma; Colon Cancer
Research Area
Oncology
Assay Name
In Vitro Ethidium Homodimer Assay (Cell Viability)
Short Description
HCT-116-cell based In Vitro Ethidium Homodimer Assay (Cell Viability)
Assay Description
Ethidium homodimer assay is another cell viability assay, which can be used to detect dead cells. Ethidium homodimer can penetrate through the cell membrane and gives red fluorescence upon binding with DNA of dead cells.
Assay Type
Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Type Details
Uncontrolled proliferation is one of the main features of cancer cells. Cell-based in vitro assays are employed to determine whether test molecules possess direct cytotoxic/antiproliferative effects in cancer cells.