HCT116 In Vitro TOTO Assay (Cell Viability)

CAT#: ITS-1022-YF965
Target Cell Organism: Human
Target Cell Alternative Name: HCT 116
Target Cell Name: HCT116
Assay Type: Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Overview
This assay is to provide HCT116-based In Vitro TOTO Assay (Cell Viability) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
HCT116
Target Cell Organism
Human
Target Cell Background
HCT 116 cell line was isolated from the colon of an adult male with colon cancer. It has a mutation in codon 13 of the ras proto-oncogene and can be d as a positive control for PCR assays of mutation in this codon.
Target Cell Alternative Name
HCT 116
Related Diseases
Colon Cancer
Research Area
Oncology
Assay Name
In Vitro TOTO Assay (Cell Viability)
Short Description
HCT116-cell based In Vitro TOTO Assay (Cell Viability)
Assay Description
The dyes in SYTOX family (blue, green, orange and red), TOTO and TO-PRO are other fluorescence dyes, which can penetrate only into dead cells to determine the cell viability.
Assay Type
Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Type Details
Uncontrolled proliferation is one of the main features of cancer cells. Cell-based in vitro assays are employed to determine whether test molecules possess direct cytotoxic/antiproliferative effects in cancer cells.
Assay Subtype
Cell Viability Assay
Assay MOA
Dye Exclusion Assays
For Research Use Only | Not For Clinical Use
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