This assay is to provide HCT116-based In Vivo Tumorigenesis Assay to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
HCT116
Target Cell Organism
Human
Target Cell Background
HCT 116 cell line was isolated from the colon of an adult male with colon cancer. It has a mutation in codon 13 of the ras proto-oncogene and can be d as a positive control for PCR assays of mutation in this codon.
Target Cell Alternative Name
HCT 116
Related Diseases
Colon Cancer
Research Area
Oncology
Assay Name
In Vivo Tumorigenesis Assay
Short Description
HCT116-cell based In Vivo Tumorigenesis Assay
Assay Description
Tumorigenicity is defined the property of a cell to form tumors when inoculated into an immunosuppressed animal model. Generally, test cells and tumor cells as positive control are administered subcutaneously into immunosuppressed nude mice. The number of animals developing tumors are compared with a positive control reference cell line.