Hepa 1-6 In Vitro Glutathione Assay (Oxidative Stress)
CAT#: ITS-1022-YF2380
Target Cell Organism: Mouse
Target Cell Alternative Name: Hepa1-6
Target Cell Name: Hepa 1-6
Assay Type: Oxidative Stress Assays
Assay Overview
This assay is to provide Hepa 1-6-based In Vitro Glutathione Assay (Oxidative Stress) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
Hepa 1-6
Target Cell Organism
Mouse
Target Cell Background
The Hepa 1-6 tumorigenic epithelial cell line is derived from liver cells of the BW7756 mouse (Mus musculus) with hepatoma. Hepa 1-6 has been negatively tested for mousepox and is widely used in mammalian liver tissue functions research.
Target Cell Alternative Name
Hepa1-6
Related Diseases
Liver Hepatoma
Research Area
Oncology
Assay Name
In Vitro Glutathione Assay (Oxidative Stress)
Short Description
Hepa 1-6-cell based In Vitro Glutathione Assay (Oxidative Stress)
Assay Type
Oxidative Stress Assays
Assay Type Details
Disturbance between the production of reactive oxygen species (ROS), free radicals and antioxidant mechanisms is defined as the oxidative stress, or more precisely, it is an imbalance between the oxidant and antioxidant state in cells. This imbalance can cause harmful effects to cells and biomolecules, which ultimately causes adverse effects in the whole organism. Oxidative imbalance can target important proteinsand lipids in cells, which can increase the risk of developing a cancer. On the other hand, increased ROS production in cancer cells by certain cancer drugs can also arrest cancer cell cycle and cause senescence and apoptosis through oxidative stress.