PharmaOnco™ DNase I

Deoxyribonuclease I (DNase I, encoded by DNASE1) is a specific endonuclease facilitating chromatin breakdown during apoptosis. It is a versatile enzyme that nonspecifically cleaves DNA to release 5'-phosphorylated di-, tri-, and oligonucleotide products. DNase-I is appropriate for tissue digestion and preparation of a single cell suspension, and has been used for the digestion of human tissues such as microglia , cartilage, colon, epithelium, liver, lung, neural , and stem cells.

Digestion of DNA

B Cells, Endothelial Colony Forming Cells (ECFCs), Neurons, Osteoblasts, T Cells

Mammalian Cell

Bovine pancreas

Immunology, Stem Cell Biology

Restrictions for research use only. Intended for use by laboratory professionals.

Stable for 12 months from date of manufacture on label.

Store at 2 - 8°C.

29.1 kDa

Lyophilized powder

Reconstitute in a balanced salt solution or buffer of choice.