PharmaOnco™ Human GITR Reporter (Luc) - HT1080 Recombinant Cell Line

This cell line expresses a surface human GITR and an NF-kappaB luciferase reporter construct that are stably integrated into the genome of HT1080.The firefly luciferase gene is controlled by 4 copies of NF-kappaB response element located upstream of the TATA promoter. Following activation by stimulants, endogenous NF-kappaB transcription factors bind to the DNA response elements to induce transcription of the luciferase gene.

Human

HT1080