PharmaOnco™ Mv1 Lu-PAI-1 Luc Reporter Cell Line, Single Clone

Creative Biolabs offers Mv1 Lu-PAI-1 Luc reporter cell line which has been engineered to express a luciferase reporter gene under the control of the PAI-1 promoter.

The Mv1 Lu-PAI-1 Luc reporter cell line is a genetically modified cell line that has been engineered to express a luciferase reporter gene under the control of the PAI-1 promoter. PAI-1, or plasminogen activator inhibitor-1, is a protein that plays a key role in regulating the fibrinolytic system in the body. This cell line can be used in a wide range of research applications, including drug discovery, signal transduction studies, and investigating the role of PAI-1 in various disease states such as thrombosis, cardiovascular disease, and cancer.

Consistent gene expression;
Reliability and reproducibility;

Functional assay

PAI-1

Human

Mv1 Lu

PAI-1 Luc Reporter is a genetically engineered cell line or animal model that contains a luciferase reporter gene under the control of the PAI-1 promoter. This reporter system allows researchers to study the activity of the PAI-1 gene by monitoring the expression of the luciferase enzyme, which emits light when a substrate is added. This can provide valuable information about the regulation of PAI-1 gene expression in response to various stimuli or conditions. The PAI-1 Luc Reporter system is commonly used in research studies related to blood coagulation, fibrinolysis, and cardiovascular diseases.

1 x 10e6 cells/vial, Frozen

Creative Biolabs provides sterility testing in accordance with USP and EP regulations. All of our sterility testing is performed in an isolator or clean room environments. The cell line has been screened using the membrane filtration testing methods to confirm the absence of aerobic, anaerobic and fungi microorganisms.

Identity testing is required for newly established cell lines. Isoenzyme analysis is used to confirm the identity of the species of a cell line. Alternative methods for identity testing include DNA fingerprinting, STR analysis and karyology.

A broad range of viruses is susceptible to affecting human cell lines. We can provide in vivo/vitro virus safety assays by utilizing various animal systems. These viruses include: adventitious viruses, bovine viruses, human and simian viruses, porcine viruses, retrovirus and rodent viruses.

We perform cell genetic stability studies under ICH guidelines. We can provide guidance on the appropriate testing program upon your requirements.

The cell line has been screened using the luciferase based mycoplasma detection kit to confirm the absence of mycoplasma species.

Dry Ice

Frozen cells should be stored in a liquid nitrogen tank (-150°C~-190°C). After thawing, cells should be immediately transferred to the appropriate culture medium and maintained under recommended culture conditions.

Frozen cells should be thawed immediately upon receipt and grown according to handling procedure to ensure cell viability and proper assay performance.
Note: Do not freeze the cells upon receipt as it may result in irreversible damage to the cell line.
Disclaimer: We cannot guarantee cell viability if the cells are not thawed immediately upon receipt and grown according to handling procedure.

Avoid multiple freeze/thaw cycles

For research use only, not for diagnostic or therapeutic use.

All of our stable cell lines meet the highest quality standards and have been confirmed to be pathogen-free.