Jeko-1 In Vitro Boyden Chamber Assay (Angiogenesis)
CAT#: ITS-0123-YF3729
Target Cell Organism: Human
Target Cell Name: Jeko-1
Assay Type: Angiogenesis Monitoring Assays
Assay Overview
This assay is to provide Jeko-1-based In Vitro Boyden Chamber Assay (Angiogenesis) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
Jeko-1
Target Cell Organism
Human
Target Cell Background
The JeKo-1 Mantle cell lymphoma (MCL) cell line was established from peripheral blood mononuclear cells of a patient with a large cell variant of MCL showing leukemic conversion.
Related Diseases
Mantle Cell Lymphoma; MCL
Research Area
Oncology
Assay Name
In Vitro Boyden Chamber Assay (Angiogenesis)
Assay Description
The Boyden chamber assay has been used to study angiogenesis by assessing endothelial cell migration.
Assay Type
Angiogenesis Monitoring Assays
Assay Type Details
Local and regional metastasis is a life-threatening condition in cancer, which is hard to control with the available cancer treatment options. In metastasis, cancer cells move away from primary tumors and travel through the blood and lymphatic system and form new tumors on other parts. A vascular network growth is important for cancer metastasis. Angiogenesis is a process that is known as the formation of new blood vessels with the help of existing blood vessels and angiogenesis has been reported to play a major role in cancer growth and metastasis. Tumors can send chemical signals to nearby normal tissues to stimulate angiogenesis. New blood vessels can feed growing tumors with nutrients and oxygen, allowing cancer cells to spread (metastasis).