Jurkat In Vitro ABTS Radical Cation Decolorization Assay (Oxidative Stress)

This assay is to provide Jurkat-based In Vitro ABTS Radical Cation Decolorization Assay (Oxidative Stress) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.

Jurkat

Human

The Jurkat cell line (originally called JM) was established in the mid-1970s from the peripheral blood of a 14-year-old boy with T cell leukemia. Different derivatives of the Jurkat cell line have been mutated to lack certain genes.

Acute Lymphoblastic Leukemia; ALL

Oncology

In Vitro ABTS Radical Cation Decolorization Assay (Oxidative Stress)

Jurkat-cell based In Vitro ABTS Radical Cation Decolorization Assay (Oxidative Stress)

It's a commonly used simple antioxidant assay. The ability of antioxidants to reduce ABTS free radical (ABTS.) to ABTS is measured in the ABTS assay.

Oxidative Stress Assays

Disturbance between the production of reactive oxygen species (ROS), free radicals and antioxidant mechanisms is defined as the oxidative stress, or more precisely, it is an imbalance between the oxidant and antioxidant state in cells. This imbalance can cause harmful effects to cells and biomolecules, which ultimately causes adverse effects in the whole organism. Oxidative imbalance can target important proteinsand lipids in cells, which can increase the risk of developing a cancer. On the other hand, increased ROS production in cancer cells by certain cancer drugs can also arrest cancer cell cycle and cause senescence and apoptosis through oxidative stress.

Antioxidant Assay