K562 In Vitro Protein Expression Analysis Assay (Immunoprecipitation)
CAT#: ITS-1022-YF198
Target Cell Organism: Human
Target Cell Alternative Name: K-562
Target Cell Name: K562
Assay Type: Gene and Protein Expression Assays
Assay Overview
This assay is to provide K562-based In Vitro Protein Expression Analysis Assay (Immunoprecipitation) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
K562
Target Cell Organism
Human
Target Cell Background
K562 cells are of the erythroleukemia type, and the cell line is derived from a 53-year-old female chronic myelogenous leukemia patient in blast crisis. The cells are non-adherent and rounded, are positive for the bcr:abl fusion gene, and bear some proteomic resemblance to both undifferentiated granulocytes and erythrocytes.
Target Cell Alternative Name
K-562
Related Diseases
Chronic Myeloid Leukemia; CML
Research Area
Oncology
Assay Name
In Vitro Protein Expression Analysis Assay (Immunoprecipitation)
Short Description
K562-cell based In Vitro Protein Expression Analysis Assay (Immunoprecipitation)
Assay Description
For protein expression, western blotting and immunoassays have provided high-quality quantitative results. 2D gel electrophoresis
Assay Type
Gene and Protein Expression Assays
Assay Type Details
Following transcription, primary transcript RNA is converted into mature RNA by post-transcriptional modifications. Post-transcriptional modification includes three major steps namely the addition of a 5'cap, addition of a 3'polyadenylation tail and RNA splicing. Stability of RNA has been considered as very important for gene expression and proteins at the post-transcriptional level.