Lipoyl Synthase-targeted RNA Modification and Metabolomics Analysis Tool
CAT#: ITS-0524-CR230
Cell Type: M2 macrophages
RNA writers: METTL14
RNA readers: HNRNPs
RNA erasers: ALKBH5
Enzymes: HDACs
RNA types: tRNA
Modification: ψ
RNA editing: A to I
Short Description
This product is a Lipoyl synthase-targeted RNA modification and metabolomics analysis tool based on the ψ (METTL14-HNRNPs-ALKBH5-HDACs-Hexynyl) modification and Gluconeogenesis-mediated (RBM9-SAM-ATP) metabolic analysis system.
RNA writers
METTL14
RNA readers
HNRNPs
RNA erasers
ALKBH5
Enzymes
HDACs
RNA types
tRNA
Modification
ψ
Label
Hexynyl
RNA editing
A to I
Cell Type
M2 macrophages
Oligonucleotide
2'-OMe, 2'dT (LNP)
RNA Construction
tRNA-ψ-METTL14-HNRNPs-ALKBH5-HDACs-Hexynyl
Substrates
SAM
Cofactors
ATP
Pathway
Gluconeogenesis
Epigenetic regulator
NSD2 overexpression
Metabolic alteration
Upregulating pentose phosphate pathway
Targeting diseases
Lung Cancer
RNA-binding proteins
RBM9
Metabolic Reprogramming
Gluconeogenesis-RBM9-SAM-ATP
Target
Lipoyl synthase
Alternative Names
Lipoyl synthase
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.