MB49 In Vitro Tumor Cell Target Expression Assay

This assay is to provide MB49-based In Vitro Tumor Cell Target Expression Assay to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.

MB49

Mouse

MB49 cells are derived from C57BL/Icrf-a' mouse bladder epithelial cells that were transformed by a single 24-hour treatment with the chemical carcinogen 7, 12-dimethylbenz[a]anthracene (DMBA) on the second day of a long term primary culture. Transformed cells transplanted into syngeneic mice were shown to generate carcinomas. While of male origin, karyotype analyses indicate the loss of the Y chromosome in 100% of the cells analyzed. This abnormality is a frequent early event in human bladder cancer.

Bladder Cancer

Oncology

In Vitro Tumor Cell Target Expression Assay

MB49-cell based In Vitro Tumor Cell Target Expression Assay

Tumor Marker Expression Assay; Inhibitory Ligand Expression Assay

Tumor Cell Analysis Assay

Use FACS technology to analyze the tumor expression markers.