MBT-2 In Vitro Ethidium Homodimer Assay (Cell Viability)

CAT#: ITS-1022-YF3382
Target Cell Organism: Mouse
Target Cell Name: MBT-2
Assay Type: Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Overview
This assay is to provide MBT-2-based In Vitro Ethidium Homodimer Assay (Cell Viability) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
MBT-2
Target Cell Organism
Mouse
Target Cell Background
MBT-2 cells are murine bladder cancer cells with epithelial characteristics. Their formation is induced by the administration of FANFT (N-[4-(5-nitro-2-furyl)-2-thiazolyl] formamide) to C3H/He mice.
Related Diseases
Bladder Cancer
Research Area
Oncology
Assay Name
In Vitro Ethidium Homodimer Assay (Cell Viability)
Short Description
MBT-2-cell based In Vitro Ethidium Homodimer Assay (Cell Viability)
Assay Description
Ethidium homodimer assay is another cell viability assay, which can be used to detect dead cells. Ethidium homodimer can penetrate through the cell membrane and gives red fluorescence upon binding with DNA of dead cells.
Assay Type
Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Type Details
Uncontrolled proliferation is one of the main features of cancer cells. Cell-based in vitro assays are employed to determine whether test molecules possess direct cytotoxic/antiproliferative effects in cancer cells.
Assay Subtype
Cell Viability Assay
Assay MOA
Dye Exclusion Assays
For Research Use Only | Not For Clinical Use
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