MECR-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR369
Cell Type: CD8 T Cells
RNA writers: METTL16
RNA readers: GF2BP1/2/3
RNA erasers: FTO
Enzymes: KMTs
RNA types: rRNA
Modification: ac4C
RNA editing: A to I
Short Description
This product is a MECR-targeted RNA modification and metabolomics analysis tool based on the ac4C (METTL16-GF2BP1/2/3-FTO-KMTs-spacer C9) modification and Fatty acid synthesis-mediated (hnRNPs-Acetyl-CoA-α-KG) metabolic analysis system.
RNA writers
METTL16
RNA readers
GF2BP1/2/3
RNA erasers
FTO
Enzymes
KMTs
RNA types
rRNA
Modification
ac4C
Label
spacer C9
RNA editing
A to I
Cell Type
CD8 T Cells
Oligonucleotide
2'-OMe, 2'dT (LNP)
RNA Construction
rRNA-ac4C-METTL16-GF2BP1/2/3-FTO-KMTs-spacer C9
Substrates
Acetyl-CoA
Cofactors
α-KG
Pathway
Fatty acid synthesis
Epigenetic regulator
KMT2D inhibition
Metabolic alteration
Upregulating glycolysis and lipids metabolism
Targeting diseases
Acute Myeloid Leukemia
RNA-binding proteins
hnRNPs
Metabolic Reprogramming
Fatty acid synthesis-hnRNPs-Acetyl-CoA-α-KG
Target
MECR
Alternative Names
MECR; CGI-63; FASN2B; NRBF1; mitochondrial trans-2-enoyl-CoA reductase; ETR1; DYTOABG
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
Online Inquiry