ModifiSite™ Alcohol Dehydrogenase Assay Kit

CAT#: ITS-1125-HM66
Product Type: Assay Kit
Species: All Species
Brand: ModifiSite
Development Stage: Research-Grade Protein & Enzyme Assay Development
Short Description
Quantifies ADH activity via NADH production.
Brand
ModifiSite
Development Stage
Research-Grade Protein & Enzyme Assay Development
Description
The ModifiSite™ Alcohol Dehydrogenase Assay Kit measures ADH activity to assess liver metabolic capacity and drug-alcohol interactions. This kinetic assay is essential for researching alcohol dependence therapies and understanding the pharmacokinetics of ethanol metabolism. It validates the impact of drugs on the liver's detoxification pathways, helping to predict potential adverse effects.
Features
Kinetic measurement of NADH production; Assessing drug-alcohol interactions and liver metabolic capacity.
Process Relevance
ADME/Tox (Metabolic Stability)
Application Stage
ADME / DMPK
Applications
Studying alcohol metabolism and liver detoxification capacity.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Absorbance at 565 nm
Sample Type
Serum, citrate-plasma, urine, cell lysate, culture medium
Research Areas
Toxicology; Addiction Research
Size
100 tests
Data Output Type
Kinetic (Enzyme Activity)
Assay Time
Results in 30 min
LOD
0.4 U/L
Species
All Species
Storage
Store at −20 °C upon receipt to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to −20 °C storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
6 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Alcohol Dehydrogenase (ADH) facilitates the oxidation of alcohols to aldehydes. It constitutes the body's primary defense against alcohol intoxication and is central to the metabolism of ethanol.
For Research Use Only | Not For Clinical Use
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