MOLT-4 In Vitro RNA Expression Analysis Assay (Cap Analysis)
CAT#: ITS-1122-YF5970
Target Cell Organism: Human
Target Cell Name: MOLT-4
Assay Type: Gene and Protein Expression Assays
Assay Overview
This assay is to provide MOLT-4-based In Vitro RNA Expression Analysis Assay (Cap Analysis) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
MOLT-4
Target Cell Organism
Human
Target Cell Background
MOLT-4 is a T lymphoblast cell line derived from the same patient as the MOLT-3 cell line. The line was established from cells taken from a 19-year-old, male patient with Acute lymphoblastic leukemia (ALL) in relapse. This cell line can be used in immunology and immune system disorder research.
Related Diseases
Acute Lymphoblastic Leukemia; ALL
Research Area
Oncology
Assay Name
In Vitro RNA Expression Analysis Assay (Cap Analysis)
Short Description
MOLT-4-cell based In Vitro RNA Expression Analysis Assay (Cap Analysis)
Assay Description
Cap analysis gene expression involves the sequencing of PCR-amplified cDNA tags obtained from the 5' end of mRNA. For the identification of starting sites of transcription, the cap analysis gene expression tech nique has become a useful platform.
Assay Type
Gene and Protein Expression Assays
Assay Type Details
Following transcription, primary transcript RNA is converted into mature RNA by post-transcriptional modifications. Post-transcriptional modification includes three major steps namely the addition of a 5'cap, addition of a 3'polyadenylation tail and RNA splicing. Stability of RNA has been considered as very important for gene expression and proteins at the post-transcriptional level.