MV-4-11 In Vitro LDH Assay (Cell Viability)

CAT#: ITS-1122-YF4315
Target Cell Organism: Human
Target Cell Alternative Name: MV(4;11)
Target Cell Name: MV-4-11
Assay Type: Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Overview
This assay is to provide MV-4-11-based In Vitro LDH Assay (Cell Viability) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
MV-4-11
Target Cell Organism
Human
Target Cell Background
A model of human AML (acute myeloid leukemia) Acute myeloid leukemia (AML) is a malignant disorder of the progenitor cells in myeloid hematopoiesis and represents a genetically heterogeneous cancer.
Target Cell Alternative Name
MV(4;11)
Related Diseases
Acute Myeloid Leukemia; AML
Research Area
Oncology
Assay Name
In Vitro LDH Assay (Cell Viability)
Short Description
MV-4-11-cell based In Vitro LDH Assay (Cell Viability)
Assay Description
Lactate dehydrogenase leakage assay (LDH assay) can also be used to determine viability of cancer cells. Upon treatment with a testing drug, if the drug can rupture the cell membrane, cells release LDH to the culture medium and released LDH can be quantified.
Assay Alternative Names
Lactate Dehydrogenase Leakage Assay
Assay Type
Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Type Details
Uncontrolled proliferation is one of the main features of cancer cells. Cell-based in vitro assays are employed to determine whether test molecules possess direct cytotoxic/antiproliferative effects in cancer cells.
Assay Subtype
Cell Viability Assay
Assay MOA
Cell-based Viability Assays Based on Cellular Enzymes and Proteins
For Research Use Only | Not For Clinical Use
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