Assay Type: Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Overview
This assay is to provide MV-4-11-based In Vitro TOTO Assay (Cell Viability) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
MV-4-11
Target Cell Organism
Human
Target Cell Background
A model of human AML (acute myeloid leukemia) Acute myeloid leukemia (AML) is a malignant disorder of the progenitor cells in myeloid hematopoiesis and represents a genetically heterogeneous cancer.
Target Cell Alternative Name
MV(4;11)
Related Diseases
Acute Myeloid Leukemia; AML
Research Area
Oncology
Assay Name
In Vitro TOTO Assay (Cell Viability)
Short Description
MV-4-11-cell based In Vitro TOTO Assay (Cell Viability)
Assay Description
The dyes in SYTOX family (blue, green, orange and red), TOTO and TO-PRO are other fluorescence dyes, which can penetrate only into dead cells to determine the cell viability.
Assay Type
Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Type Details
Uncontrolled proliferation is one of the main features of cancer cells. Cell-based in vitro assays are employed to determine whether test molecules possess direct cytotoxic/antiproliferative effects in cancer cells.