NCI-H441 In Vitro Real-time Monitoring of Cell Migration Assay

This assay is to provide NCI-H441-based In Vitro Real-time Monitoring of Cell Migration Assay to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.

NCI-H441

Human

NCI-H441 [H441] cells were isolated in 1982 from the pericardial fluid of a male patient with papillary adenocarcinoma of the lung. Use these cells as a transfection host for expression of pulmonary surfactant protein (SP-B).

H441

Lung Cancer

Oncology

In Vitro Real-time Monitoring of Cell Migration Assay

Real-time monitoring assays have permitted more easy and reliable ways for the detection of cancer cell invasion and migra tion (real-time monitoring).

Cell Migration and Invasion Assays

The movement of cancer cells and formation of tumors in neighboring tissue is a sequential cascade known as invasion-metastatic cascade, which includes cancer cell invasion through extracellular matrix (ECM), intravasation into blood and colonization at sites after they exit from blood circulation. Migration and invasion are two dif ferent processes where, cell migration involves movement of cells without passing through a barrier such as ECM, whereas cell invasion involves passing through a barrier such as ECM while destroying it.

Cell Migration Assay

Cell Migration Assay