OMT-targeted RNA Modification and Metabolomics Analysis Tool
CAT#: ITS-0524-CR249
Cell Type: CD8 T Cells
RNA writers: METTL14
RNA readers: YTHDF2
RNA erasers: ALKBH5
Enzymes: HDACs
RNA types: mRNAs
Modification: ac4C
RNA editing: A to I
Short Description
This product is a OMT-targeted RNA modification and metabolomics analysis tool based on the ac4C (METTL14-YTHDF2-ALKBH5-HDACs-MGB) modification and Glycogen synthesis-mediated (hnRNPs-SAM-ADP) metabolic analysis system.
RNA writers
METTL14
RNA readers
YTHDF2
RNA erasers
ALKBH5
Enzymes
HDACs
RNA types
mRNAs
Modification
ac4C
Label
MGB
RNA editing
A to I
Cell Type
CD8 T Cells
Oligonucleotide
2'-OMe (cationic lipoplex)
RNA Construction
mRNAs-ac4C-METTL14-YTHDF2-ALKBH5-HDACs-MGB
Substrates
SAM
Cofactors
ADP
Pathway
Glycogen synthesis
Epigenetic regulator
KMT2D inhibition
Metabolic alteration
Upregulating glycolysis and lipids metabolism
Targeting diseases
Glioblastoma
RNA-binding proteins
hnRNPs
Metabolic Reprogramming
Glycogen synthesis-hnRNPs-SAM-ADP
Target
OMT
Alternative Names
O-methyltransferase (OMT
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.