Short Description
For the precise and reliable visualization of AIMP2/JTV1, this IHC kit offers a complete set of ready-to-use reagents and an optimized protocol for consistent and accurate staining.
Description
JTV1, also named p38 or AIMP2, was first identified as a factor associated with a macromolecular protein complex consisting of several aminoacyl-tRNA synthetases. It is a scaffold protein required for the assembly and stability of the multi-tRNA synthetase complex. JTV1 mediates TGF-beta signaling and regulates MYC during lung differentiation. It blocks MDM2-mediated ubiquitination and degradation of p53/TP53 and functions as a proapoptotic factor.
Features
Ready to use
High Sensitivity Streptavidin (HSS) increases detection sensitivity
Suitable for tissue sections & cytospin preparations
Pre-diluted reagents minimize hands-on time
Optimizes mouse, rabbit, rat, goat, or sheep IgG primary antibody staining
Reactivity
Human, Mouse, Rat
Analytical Method
Immunohistochemistry
Datasheet