Short Description
For the precise and reliable visualization of BAK, this IHC kit offers a complete set of ready-to-use reagents and an optimized protocol for consistent and accurate staining.
Description
The protein encoded by this gene is part of the BCL2 protein family, which regulates apoptosis. BCL2 family members can form oligomers or heterodimers that either promote or inhibit apoptosis. This protein localizes to mitochondria and induces apoptosis by interacting with and accelerating the opening of the mitochondrial voltage-dependent anion channel, leading to membrane potential loss and cytochrome c release. It also interacts with tumor suppressor P53 following cellular stress.
Features
Ready to use
High Sensitivity Streptavidin (HSS) increases detection sensitivity
Suitable for tissue sections & cytospin preparations
Pre-diluted reagents minimize hands-on time
Optimizes mouse, rabbit, rat, goat, or sheep IgG primary antibody staining
Reactivity
Human, Mouse, Rat
Analytical Method
Immunohistochemistry
Datasheet
