OncoIHC™ CTNNA1 Ready-To-Use IHC Kit

For efficient CTNNA1 staining, deploy this pre-prepared IHC kit, designed with all necessary reagents for a seamless antigen retrieval to coverslip procedure.

Alpha catenin is a vital component of adherens junctions, linking E-cadherin-β-catenin complexes to the actin cytoskeleton. It also recruits additional proteins to form intercellular junctions. There are three forms of alpha catenin in humans: alpha-E, alpha-N, and alpha-T. These isoforms have similar amino-acid sequences but differ in tissue distribution. Alpha-E is found universally, alpha-N is specific to neurons, and alpha-T is primarily present in heart tissue. A reduction in alpha-E-catenin is commonly observed in various cancers, such as those of the breast, colon, stomach, esophagus, bladder, and liver, and is often correlated with tumor differentiation and metastasis.

Ready to use
High Sensitivity Streptavidin (HSS) increases detection sensitivity
Suitable for tissue sections & cytospin preparations
Pre-diluted reagents minimize hands-on time
Optimizes mouse, rabbit, rat, goat, or sheep IgG primary antibody staining

IHC

CTNNA1

Human, Mouse, Rat

Immunohistochemistry

FFPE tissue

Primary Antibody
Secondary Antibody
Antigen Unmasking Buffer
Washing Buffer
Blocking Buffer
Color Development Reagent 1
Color Development Reagent 170
Signal Amplification Reagent
Contrast Staining Agent
Preservation Matrix

To ensure the preservation of their functional properties, all reagents within this kit must be maintained at a temperature between 2°C and 8°C. Under these storage conditions, the kit will retain its effectiveness for a period of 6 to 12 months following receipt.

Alpha E catenin; Alpha E-Catenin; Cadherin associated protein; CAP102; Catenin alpha 1; CTNNA1

Creative Biolabs control slides are prepared using top quality tissues that have been processed, embedded and sectioned following standard operating procedure. We provide the following antigen (tissue) controls:
- Positive control: a section from a tissue known to express the protein of interest.
- Negative control: a section from a tissue known not to express the target antigen.
- Endogenous tissue background control: a section from the tissue that doesn't have a primary antibody applied.

Creative Biolabs also offers biospecimen including formalin fixed paraffin embedded (FFPE) tissue blocks, fresh or snap frozen tissue blocks, tissue microarray (TMA) slides. Please contact us to request a customized price quotation.

Tissue Fixative Solution (Specified, depends on antigen type and tissue source)
Tissue Processing Kit (Includes specialized media for tissue collection, isolation, and dissociation)
Tissue Embedding Media
Tissue Staining Kit (Optional)