Short Description
Achieve efficient GATM staining with this pre-prepared IHC kit, facilitating a seamless antigen retrieval to coverslip process.
Description
GATM, or AGAT, is an enzyme responsible for producing ornithine and guanidinoacetate (GAA) from arginine and glycine. It is crucial for creatine synthesis. Deficiency in GATM during infancy leads to neurodevelopmental delays. In adults, GATM is predominantly expressed in the kidney and pancreas, and reduced levels of this protein are associated with proximal tubule damage, making it a marker for kidney damage.
Features
Ready to use
High Sensitivity Streptavidin (HSS) increases detection sensitivity
Suitable for tissue sections & cytospin preparations
Pre-diluted reagents minimize hands-on time
Optimizes mouse, rabbit, rat, goat, or sheep IgG primary antibody staining
Reactivity
Human, Mouse, Rat
Analytical Method
Immunohistochemistry
Datasheet
