OncoIHC™ Histone H1.0 Ready-To-Use IHC Kit

Ensure consistent Histone H1.0 staining with this pre-prepared IHC kit, supplying reagents tailored for efficient, start-to-finish staining.

Histones are fundamental nuclear proteins essential for the formation of nucleosomes, the structural units of chromosomal fibers in eukaryotic cells. Nucleosomes consist of approximately 146 base pairs (bp) of DNA wrapped around a histone octamer, which includes two copies of each of the four core histones: H2A, H2B, H3, and H4. Linker histone H1 interacts with the DNA between nucleosomes, facilitating the formation of higher-order chromatin structures. Linker histones, such as H1F0, are critical for maintaining chromatin compaction, especially in cells that are in the terminal stages of differentiation or have low cell division rates. H1.0 (also known as H1F0 or H1FV) is ubiquitously expressed in various tissues across vertebrates.

Ready to use
High Sensitivity Streptavidin (HSS) increases detection sensitivity
Suitable for tissue sections & cytospin preparations
Pre-diluted reagents minimize hands-on time
Optimizes mouse, rabbit, rat, goat, or sheep IgG primary antibody staining

IHC

Histone

Human, Mouse, Rat

Immunohistochemistry

FFPE tissue

Primary Antibody
Secondary Antibody
Antigen Unmasking Buffer
Washing Buffer
Blocking Buffer
Color Development Reagent 1
Color Development Reagent 288
Signal Amplification Reagent
Contrast Staining Agent
Preservation Matrix

To ensure the preservation of their functional properties, all reagents within this kit must be maintained at a temperature between 2°C and 8°C. Under these storage conditions, the kit will retain its effectiveness for a period of 6 to 12 months following receipt.

H10; H1F0; H1FV; histone; Histone H1; Histone H1(0); Histone H1.0

Creative Biolabs control slides are prepared using top quality tissues that have been processed, embedded and sectioned following standard operating procedure. We provide the following antigen (tissue) controls:
- Positive control: a section from a tissue known to express the protein of interest.
- Negative control: a section from a tissue known not to express the target antigen.
- Endogenous tissue background control: a section from the tissue that doesn't have a primary antibody applied.

Creative Biolabs also offers biospecimen including formalin fixed paraffin embedded (FFPE) tissue blocks, fresh or snap frozen tissue blocks, tissue microarray (TMA) slides. Please contact us to request a customized price quotation.

Tissue Fixative Solution (Specified, depends on antigen type and tissue source)
Tissue Processing Kit (Includes specialized media for tissue collection, isolation, and dissociation)
Tissue Embedding Media
Tissue Staining Kit (Optional)